Congratulations to the winners!
Veronica Sandroni for the AIRWISE project and Jan Berkehan Erkilic, MD MPH for MetaboPsy!
AIRWISE studies the impact of air pollution on the risk and progression of psychiatric disorders. The project’s institutional referent is Baptiste Pignon.
Urbanicity is a recognized risk factor for several psychiatric disorders (psychoses, mood disorders, autism spectrum disorders). Air pollution (AP) is an environmental factor potentially responsible for this association, although still poorly understood.
Objectives :
- to study the impact of exposure to different pollutants on the risk of severe psychiatric disorders,
- to identify periods of vulnerability to AP,
- to determine the clinical and biological profiles linked to exposure to AP,
- to analyze the effect of AP on the severity and evolution of psychiatric disorders, as well as on sub-clinical symptoms.
MetaboPsy studies immunometabolic abnormalities in major mood and psychotic disorders. The project’s institutional referent is Ophelia Godin.
People with major psychiatric disorders are at increased risk of metabolic disorders (type 2 diabetes, obesity, dyslipidemia), contributing to a 10-20 year reduced life expectancy. Understanding this comorbidity is crucial to improving prevention and early treatment.
Some recent studies suggest that a subgroup of patients with immunometabolic abnormalities present specific symptoms (hyperphagia, weight gain, hypersomnia, fatigue, anhedonia). However, research remains limited.
Objectives :
- identify the specific symptoms associated with metabolic abnormalities in different psychiatric disorders,
- study the long-term links between immunometabolic derangements and atypical symptoms,
- assess the impact of metabolic health on treatment response,
- explore brain alterations in patients with immunometabolic syndrome,
- define a clinico-biological signature of metabolic health in severe psychiatric disorders.